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Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1)

Polyvinyl alcohol (PVAL) has not been investigated in a binary formulation as a concentration-enhancing polymer owing to its high melting point/high viscosity and poor organic solubility. Due to the unique attributes of the KinetiSol® dispersing (KSD) technology, PVAL has been enabled for this appli...

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Dettagli Bibliografici
Pubblicato in:AAPS PharmSciTech
Autori principali: Brough, Chris, Miller, Dave A., Keen, Justin M., Kucera, Shawn A., Lubda, Dieter, Williams, Robert O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766132/
https://ncbi.nlm.nih.gov/pubmed/26637232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0458-y
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