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Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2)

The KinetiSol® Dispersing (KSD) technology has enabled the investigation into the use of polyvinyl alcohol (PVAL) as a concentration enhancing polymer for amorphous solid dispersions. Our previous study revealed that the 88% hydrolyzed grade of PVAL was optimal for itraconazole (ITZ) amorphous compo...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Brough, Chris, Miller, Dave A., Ellenberger, Daniel, Lubda, Dieter, Williams, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766124/
https://ncbi.nlm.nih.gov/pubmed/26863889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-016-0490-6
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