Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling

Neuronal senescence caused by diabetic neuropathy is considered a common complication of diabetes mellitus. Neuronal senescence leads to the secretion of pro-inflammatory cytokines, the production of reactive oxygen species, and the alteration of cellular homeostasis. Agmatine, which is biosynthesiz...

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Detalhes bibliográficos
Publicado no:Exp Neurobiol
Main Authors: Song, Juhyun, Lee, Byeori, Kang, Somang, Oh, Yumi, Kim, Eosu, Kim, Chul-Hoon, Song, Ho-Taek, Lee, Jong Eun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Brain and Neural Science 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766111/
https://ncbi.nlm.nih.gov/pubmed/26924930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2016.25.1.24
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