Hyperthermic Laser Ablation of Recurrent Glioblastoma Leads to Temporary Disruption of the Peritumoral Blood Brain Barrier

BACKGROUND: Poor central nervous system penetration of cytotoxic drugs due to the blood brain barrier (BBB) is a major limiting factor in the treatment of brain tumors. Most recurrent glioblastomas (GBM) occur within the peritumoral region. In this study, we describe a hyperthemic method to induce t...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Leuthardt, Eric C., Duan, Chong, Kim, Michael J., Campian, Jian L., Kim, Albert H., Miller-Thomas, Michelle M., Shimony, Joshua S., Tran, David D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766093/
https://ncbi.nlm.nih.gov/pubmed/26910903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148613
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