SCIDOT-43. FINAL DATA ANALYSIS OF A PILOT STUDY TESTING THE EFFICACY OF USING LASER INTERSTITIAL THERMAL THERAPY (LITT) TO INDUCE TEMPORARY DISRUPTION OF THE PERITUMORAL BLOOD BRAIN BARRIER (BBB) TO IMPROVE EFFECTIVENESS OF BBB-IMPERMEANT CHEMOTHERAPY IN RECURRENT GLIOBLASTOMA

BACKGROUND: Poor CNS drug delivery is a major limiting factor in GBM therapy. Since most recurrences occur peritumorally where infiltrating glioma cells reside, peritumoral BBB disruption may help improve drug delivery and efficacy. LITT, a minimally invasive cytoreductive treatment for brain tumors...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Tran, David, Campian, Jian, Shimony, Joshua, Kim, Albert, Ansstas, George, Leuthardt, Eric
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847033/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1179
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