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Poor Long-Term Efficacy of Prevnar-13 in Sickle Cell Disease Mice Is Associated with an Inability to Sustain Pneumococcal-Specific Antibody Titers

BACKGROUND: One of the most common causes of morbidity and mortality in children with sickle cell disease (SCD) is infection with the pneumococcal bacterium (Streptococcus pneumoniae). Unfortunately, the polysaccharide-conjugate vaccine appears to be less effective in individuals with SCD when compa...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Szczepanek, Steven M., Roberts, Sean, Rogers, Kara, Cotte, Christina, Adami, Alexander J., Bracken, Sonali J., Salmon, Sharon, Secor, Eric R., Thrall, Roger S., Andemariam, Biree, Metzger, Dennis W.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766082/
https://ncbi.nlm.nih.gov/pubmed/26910228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149261
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