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Poor Long-Term Efficacy of Prevnar-13 in Sickle Cell Disease Mice Is Associated with an Inability to Sustain Pneumococcal-Specific Antibody Titers
BACKGROUND: One of the most common causes of morbidity and mortality in children with sickle cell disease (SCD) is infection with the pneumococcal bacterium (Streptococcus pneumoniae). Unfortunately, the polysaccharide-conjugate vaccine appears to be less effective in individuals with SCD when compa...
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出版年: | PLoS One |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766082/ https://ncbi.nlm.nih.gov/pubmed/26910228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149261 |
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