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How to assess the binding strength of antibodies elicited by vaccination against HIV and other viruses

Vaccines that protect against viral infections generally induce neutralizing antibodies. When vaccines are evaluated, the need arises to assess the affinity maturation of the antibody responses. Binding titers of polyclonal sera depend not only on the affinities of the constituent antibodies but als...

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Detalhes bibliográficos
Publicado no:Expert Rev Vaccines
Autor principal: Klasse, P.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766047/
https://ncbi.nlm.nih.gov/pubmed/26641943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2016.1128831
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