Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder

Conventional antidepressants require 2–8 weeks for a full clinical response. In contrast, two rapidly acting antidepressant interventions, low-dose ketamine and sleep deprivation (SD) therapy, act within hours to robustly decrease depressive symptoms in a subgroup of major depressive disorder (MDD)...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Bunney, BG, Li, JZ, Walsh, DM, Stein, R, Vawter, MP, Cartagena, P, Barchas, JD, Schatzberg, AF, Myers, RM, Watson, SJ, Akil, H, Bunney, WE
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765913/
https://ncbi.nlm.nih.gov/pubmed/25349171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.138
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