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Ketamine Influences CLOCK:BMAL1 Function Leading to Altered Circadian Gene Expression

Major mood disorders have been linked to abnormalities in circadian rhythms, leading to disturbances in sleep, mood, temperature, and hormonal levels. We provide evidence that ketamine, a drug with rapid antidepressant effects, influences the function of the circadian molecular machinery. Ketamine m...

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Detalhes bibliográficos
Main Authors: Bellet, Marina M., Vawter, Marquis P., Bunney, Blynn G., Bunney, William E., Sassone-Corsi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161090/
https://ncbi.nlm.nih.gov/pubmed/21887357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023982
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