Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro

BACKGROUND: Aquaporins (AQP) are water channel proteins that enable fluid fluxes across cell membranes, important for homeostasis of the tissue environment and for cell migration. AQP1 knockout mouse models of human cancers showed marked inhibition of tumor-induced angiogenesis, and in pre-clinical...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Autores principales: Dorward, Hilary S., Du, Alice, Bruhn, Maressa A., Wrin, Joseph, Pei, Jinxin V., Evdokiou, Andreas, Price, Timothy J., Yool, Andrea J., Hardingham, Jennifer E.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765103/
https://ncbi.nlm.nih.gov/pubmed/26912239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0310-6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares