The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses

Mutations in the Tulp1 gene cause severe, early-onset retinitis pigmentosa (RP14) in humans. In the retina, Tulp1 is mainly expressed in photoreceptors that use ribbon synapses to communicate with the inner retina. In the present study, we demonstrate that Tulp1 is highly enriched in the periactive...

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Publicado no:J Neurosci
Main Authors: Wahl, Silke, Magupalli, Venkat Giri, Dembla, Mayur, Katiyar, Rashmi, Schwarz, Karin, Köblitz, Louise, Alpadi, Kannan, Krause, Elmar, Rettig, Jens, Sung, Ching-Hwa, Goldberg, Andrew F. X., Schmitz, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764665/
https://ncbi.nlm.nih.gov/pubmed/26911694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2275-15.2016
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