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A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
CRM1 is a highly conserved, RanGTPase-driven exportin that carries proteins and RNPs from the nucleus to the cytoplasm. We now explored the cargo-spectrum of CRM1 in depth and identified surprisingly large numbers, namely >700 export substrates from the yeast S. cerevisiae, ≈1000 from Xenopus ooc...
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| Publicado en: | eLife |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764573/ https://ncbi.nlm.nih.gov/pubmed/26673895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11466 |
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