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Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel
Down syndrome (DS), caused by trisomy of human chromosome 21 (Hsa21), is the most common cause of congenital heart defects (CHD), yet the genetic and mechanistic causes of these defects remain unknown. To identify dosage-sensitive genes that cause DS phenotypes, including CHD, we used chromosome eng...
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| Publicat a: | eLife |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764572/ https://ncbi.nlm.nih.gov/pubmed/26765563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11614 |
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