Antenatal Hypoxia Induces Epigenetic Repression of Glucocorticoid Receptor and Promotes Ischemic-Sensitive Phenotype in the Developing Heart

Large studies in humans and animals have demonstrated a clear association of an adverse intrauterine environment with an increased risk of cardiovascular disease later in life. Yet mechanisms remain largely elusive. The present study tested the hypothesis that gestational hypoxia leads to promoter h...

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Publicado en:J Mol Cell Cardiol
Autores principales: Xiong, Fuxia, Lin, Thant, Song, Minwoo, Ma, Qingyi, Martinez, Shannalee R., Lv, Juanxiu, MataGreenwood, Eugenia, Xiao, Daliao, Xu, Zhice, Zhang, Lubo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764467/
https://ncbi.nlm.nih.gov/pubmed/26779948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.003
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