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Constitutively Elevated Blood Serotonin Is Associated with Bone Loss and Type 2 Diabetes in Rats
Reduced peripheral serotonin (5HT) in mice lacking tryptophan hydroxylase (TPH1), the rate limiting enzyme for 5HT synthesis, was reported to be anabolic to the skeleton. However, in other studies TPH1 deletion either had no bone effect or an age dependent inhibition of osteoclastic bone resorption....
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Gepubliceerd in: | PLoS One |
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Hoofdauteurs: | , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Public Library of Science
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764355/ https://ncbi.nlm.nih.gov/pubmed/26907598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150102 |
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