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Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity
PURPOSE: The purpose of this study was to explore the effect of heparin on bone morphogenetic protein 6 (BMP6) osteogenic activity. METHODS: Western blot analysis was used to confirm the binding of BMP6 to heparin and to observe its effect on BMP6 signaling in C2C12-BRE-Luc myoblasts. Real-time RT-P...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580086/ https://ncbi.nlm.nih.gov/pubmed/23307015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-012-1714-3 |
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