Constitutively Elevated Blood Serotonin Is Associated with Bone Loss and Type 2 Diabetes in Rats

Reduced peripheral serotonin (5HT) in mice lacking tryptophan hydroxylase (TPH1), the rate limiting enzyme for 5HT synthesis, was reported to be anabolic to the skeleton. However, in other studies TPH1 deletion either had no bone effect or an age dependent inhibition of osteoclastic bone resorption....

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Erjavec, Igor, Bordukalo-Niksic, Tatjana, Brkljacic, Jelena, Grcevic, Danka, Mokrovic, Gordana, Kesic, Maja, Rogic, Dunja, Zavadoski, William, Paralkar, Vishwas M., Grgurevic, Lovorka, Trkulja, Vladimir, Cicin-Sain, Lipa, Vukicevic, Slobodan
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764355/
https://ncbi.nlm.nih.gov/pubmed/26907598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150102
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