Constitutively Elevated Blood Serotonin Is Associated with Bone Loss and Type 2 Diabetes in Rats

Reduced peripheral serotonin (5HT) in mice lacking tryptophan hydroxylase (TPH1), the rate limiting enzyme for 5HT synthesis, was reported to be anabolic to the skeleton. However, in other studies TPH1 deletion either had no bone effect or an age dependent inhibition of osteoclastic bone resorption....

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Erjavec, Igor, Bordukalo-Niksic, Tatjana, Brkljacic, Jelena, Grcevic, Danka, Mokrovic, Gordana, Kesic, Maja, Rogic, Dunja, Zavadoski, William, Paralkar, Vishwas M., Grgurevic, Lovorka, Trkulja, Vladimir, Cicin-Sain, Lipa, Vukicevic, Slobodan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764355/
https://ncbi.nlm.nih.gov/pubmed/26907598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150102
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