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On the validity of within-nuclear-family genetic association analysis in samples of extended families

Splitting extended families into their component nuclear families to apply a genetic association method designed for nuclear families is a widespread practice in familial genetic studies. Dependence among genotypes and phenotypes of nuclear families from the same extended family arises because of ge...

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Detalhes bibliográficos
Publicado no:Stat Appl Genet Mol Biol
Main Authors: Bureau, Alexandre, Duchesne, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764343/
https://ncbi.nlm.nih.gov/pubmed/26544107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/sagmb-2015-0056
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