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A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity

To evaluate drug and metabolite efficacy on a target organ, it is essential to include metabolic function of hepatocytes, and to evaluate metabolite influence on both hepatocytes and the target of interest. Herein, we have developed a two-chamber microfabricated device separated by a membrane enabli...

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Detalhes bibliográficos
Publicado no:Technology (Singap World Sci)
Main Authors: Bale, Shyam Sundhar, Sridharan, Gautham Vivek, Golberg, Inna, Prodanov, Ljupcho, McCarty, William J., Usta, Osman Berk, Jindal, Rohit, Yarmush, Martin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764261/
https://ncbi.nlm.nih.gov/pubmed/26925437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S2339547815200034
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