A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents

The innate immune cell sensor leucine-rich–containing family, pyrin domain containing 3 (NLRP3) inflammasome controls the activation of caspase-1, and the release of proinflammatory cytokines interleukin (IL)-1β and IL-18. The NLRP3 inflammasome is implicated in adipose tissue inflammation and the p...

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Bibliographic Details
Published in:Diabetes
Main Authors: Kursawe, Romy, Dixit, Vishwa D., Scherer, Philipp E., Santoro, Nicola, Narayan, Deepak, Gordillo, Ruth, Giannini, Cosimo, Lopez, Ximena, Pierpont, Bridget, Nouws, Jessica, Shulman, Gerald I., Caprio, Sonia
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2016
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764142/
https://ncbi.nlm.nih.gov/pubmed/26718495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1478
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