Continuous AMD3100 Treatment Worsens Renal Fibrosis through Regulation of Bone Marrow Derived Pro-Angiogenic Cells Homing and T-Cell-Related Inflammation

AMD3100 is a small molecule inhibitor of chemokine receptor type 4 (CXCR4), which is located in the cell membranes of CD34+ cells and a variety of inflammatory cells and has been reported to reduce organ fibrosis in the lung, liver and myocardium. However, the effect of AMD3100 on renal fibrosis is...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Yang, Juan, Zhu, Fengming, Wang, Xiaohui, Yao, Weiqi, Wang, Meng, Pei, Guangchang, Hu, Zhizhi, Guo, Yujiao, Zhao, Zhi, Wang, Pengge, Mou, Jingyi, Sun, Jie, Zeng, Rui, Xu, Gang, Liao, Wenhui, Yao, Ying
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763993/
https://ncbi.nlm.nih.gov/pubmed/26900858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149926
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