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Excessive α-tocopherol exacerbates microglial activation and brain injury caused by acute ischemic stroke
The vitamin E family includes both tocopherols and tocotrienols, where α-tocopherol (αTOC) is the most bioavailable form. Clinical trials testing the therapeutic efficacy of high-dose αTOC against stroke have largely failed or reported negative outcomes when a “more is better” approach to supplement...
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| Publicado no: | FASEB J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763884/ https://ncbi.nlm.nih.gov/pubmed/25411436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-263723 |
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