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CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue

Adipose tissue (AT) inflammation during obesity is mediated by immune cells and closely correlates with systemic insulin resistance. In lean AT, eosinophils are present in low but significant numbers and capable of promoting alternative macrophage activation in an IL-4/IL-13-dependent manner. In WT...

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Podrobná bibliografie
Vydáno v:J Leukoc Biol
Hlavní autoři: Bolus, W. Reid, Gutierrez, Dario A., Kennedy, Arion J., Anderson-Baucum, Emily K., Hasty, Alyssa H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763864/
https://ncbi.nlm.nih.gov/pubmed/25934927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0115-018R
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