Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3′, 3′-cGAMP)

Over 30 years ago, GGDEF domain-containing enzymes were shown to be diguanylate cyclases that produce cyclic di-GMP (cdiG), a second messenger that modulates the key bacterial lifestyle transition from a motile to sessile biofilm-forming state. Since then, the ubiquity of genes encoding GGDEF protei...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hallberg, Zachary F., Wang, Xin C., Wright, Todd A., Nan, Beiyan, Ad, Omer, Yeo, Jongchan, Hammond, Ming C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763787/
https://ncbi.nlm.nih.gov/pubmed/26839412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515287113
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