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Targeting the Gdnf Gene in peritubular myoid cells disrupts undifferentiated spermatogonial cell development
Spermatogonial stem cells (SSCs) are a subpopulation of undifferentiated spermatogonia located in a niche at the base of the seminiferous epithelium delimited by Sertoli cells and peritubular myoid (PM) cells. SSCs self-renew or differentiate into spermatogonia that proliferate to give rise to sperm...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763785/ https://ncbi.nlm.nih.gov/pubmed/26831079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517994113 |
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