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Targeting the Gdnf Gene in peritubular myoid cells disrupts undifferentiated spermatogonial cell development

Spermatogonial stem cells (SSCs) are a subpopulation of undifferentiated spermatogonia located in a niche at the base of the seminiferous epithelium delimited by Sertoli cells and peritubular myoid (PM) cells. SSCs self-renew or differentiate into spermatogonia that proliferate to give rise to sperm...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Liang-Yu, Willis, William D., Eddy, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763785/
https://ncbi.nlm.nih.gov/pubmed/26831079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517994113
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