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Optimizing clinical trial design for multiple system atrophy: lessons from the rifampicin study

Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by autonomic failure and parkinsonism/ataxia; no treatment exists to slow disease progression. A number of factors have prevented or compromised trials targeting disease modification. A major hurdle has been uncertaint...

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Bibliografske podrobnosti
izdano v:Clin Auton Res
Main Authors: Singer, Wolfgang, Low, Phillip A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763681/
https://ncbi.nlm.nih.gov/pubmed/25763826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10286-015-0281-2
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