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Efficacy and safety of rifampicin for multiple system atrophy: a randomised, double-blind, placebo-controlled trial
BACKGROUND: No available treatments slow or halt progression of multiple system atrophy, which is a rare, progressive, fatal neurological disorder. In a mouse model of multiple system atrophy, rifampicin inhibited formation of α-synuclein fibrils, the neuropathological hallmark of the disease. We ai...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4030757/ https://ncbi.nlm.nih.gov/pubmed/24507091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(13)70301-6 |
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