ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex

BACKGROUND: The Cohesin complex that holds sister chromatins together until anaphase is comprised of three core subunits: Smc1 and Smc3, two long-rod-shaped proteins with an ABC-like ATPase head (nucleotide-binding domain [NBD]) and a dimerization domain linked by a 50 nm long intra-molecular antipa...

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Publicado no:Curr Biol
Main Authors: Hu, Bin, Itoh, Takehiko, Mishra, Ajay, Katoh, Yuki, Chan, Kok-Lung, Upcher, William, Godlee, Camilla, Roig, Maurici B., Shirahige, Katsuhiko, Nasmyth, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763544/
https://ncbi.nlm.nih.gov/pubmed/21185190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.12.004
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