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Control of βAR- and N-methyl-D-aspartate (NMDA) Receptor-Dependent cAMP Dynamics in Hippocampal Neurons

Norepinephrine, a neuromodulator that activates β-adrenergic receptors (βARs), facilitates learning and memory as well as the induction of synaptic plasticity in the hippocampus. Several forms of long-term potentiation (LTP) at the Schaffer collateral CA1 synapse require stimulation of both βARs and...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Chay, Andrew, Zamparo, Ilaria, Koschinski, Andreas, Zaccolo, Manuela, Blackwell, Kim T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763502/
https://ncbi.nlm.nih.gov/pubmed/26901880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004735
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