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Identification of Neurodegenerative Factors Using Translatome-Regulatory Network Analysis

For degenerative disorders of the central nervous system, the major obstacle to therapeutic advancement has been the challenge of identifying the key molecular mechanisms underlying neuronal loss. We developed a combinatorial approach including translational profiling and brain regulatory network an...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Brichta, Lars, Shin, William, Jackson-Lewis, Vernice, Blesa, Javier, Yap, Ee-Lynn, Walker, Zachary, Zhang, Jack, Roussarie, Jean-Pierre, Alvarez, Mariano J., Califano, Andrea, Przedborski, Serge, Greengard, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763340/
https://ncbi.nlm.nih.gov/pubmed/26214373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4070
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