Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy

Mesenchymal stem cells (MSCs)-based therapy provides a promising avenue for the management of peripheral arterial disease (PAD). However, engrafted MSCs are subjected to acute cell death in the ischemic microenvironment. Apelin has been shown to protect bone marrow MSCs against apoptosis although th...

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Pubblicato in:Sci Rep
Autori principali: Liang, Dong, Han, Dong, Fan, Weiwei, Zhang, Ran, Qiao, Hongyu, Fan, Miaomiao, Su, Tao, Ma, Sai, Li, Xiujuan, Chen, Jiangwei, Wang, Yabin, Ren, Jun, Cao, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763210/
https://ncbi.nlm.nih.gov/pubmed/26902855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21914
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