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BRCA1 inhibits AR–mediated proliferation of breast cancer cells through the activation of SIRT1
Breast cancer susceptibility gene 1 (BRCA1) is a tumor suppressor protein that functions to maintain genomic stability through critical roles in DNA repair, cell-cycle arrest, and transcriptional control. The androgen receptor (AR) is expressed in more than 70% of breast cancers and has been implica...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763204/ https://ncbi.nlm.nih.gov/pubmed/26902145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22034 |
| Oznake: |
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