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A potential therapeutic peptide-based neutralizer that potently inhibits Shiga toxin 2 in vitro and in vivo
Shiga toxin 2 (Stx2) is a major virulence factor in infections with Stx-producing Escherichia coli (STEC), which can cause serious clinical complications in humans, such as hemolytic uremic syndrome (HUS). Recently, we screened and identified two peptide-based Stx2 neutralizers, TF-1 and WA-8, which...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763182/ https://ncbi.nlm.nih.gov/pubmed/26903273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21837 |
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