Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and t...

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Bibliografische gegevens
Gepubliceerd in:Stem Cells Int
Hoofdauteurs: Hermann, Andreas, Kim, Jeong Beom, Srimasorn, Sumitra, Zaehres, Holm, Reinhardt, Peter, Schöler, Hans R., Storch, Alexander
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763001/
https://ncbi.nlm.nih.gov/pubmed/26977154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4736159
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