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Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors
Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and t...
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出版年: | Stem Cells Int |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Hindawi Publishing Corporation
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4763001/ https://ncbi.nlm.nih.gov/pubmed/26977154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4736159 |
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