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Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and t...

詳細記述

保存先:
書誌詳細
出版年:Stem Cells Int
主要な著者: Hermann, Andreas, Kim, Jeong Beom, Srimasorn, Sumitra, Zaehres, Holm, Reinhardt, Peter, Schöler, Hans R., Storch, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763001/
https://ncbi.nlm.nih.gov/pubmed/26977154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4736159
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