Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

Drug resistance and tolerance greatly diminish the therapeutic potential of antibiotics against pathogens. Antibiotic tolerance by bacterial biofilms often leads to persistent infections, but its mechanisms are unclear. Here we use a proteomics approach, pulsed stable isotope labelling with amino ac...

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Pubblicato in:Nat Commun
Autori principali: Chua, Song Lin, Yam, Joey Kuok Hoong, Hao, Piliang, Adav, Sunil S., Salido, May Margarette, Liu, Yang, Givskov, Michael, Sze, Siu Kwan, Tolker-Nielsen, Tim, Yang, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762895/
https://ncbi.nlm.nih.gov/pubmed/26892159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10750
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