DDX5 and its associated lncRNA Rmrp modulate Th17 cell effector functions

Th17 lymphocytes protect mucosal barriers from infections, but also contribute to multiple chronic inflammatory diseases. Their differentiation is controlled by RORγt, a ligand-regulated nuclear receptor. We identified the DEAD-box RNA helicase DDX5 as a RORγt partner that coordinates transcription...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Huang, Wendy, Thomas, Benjamin, Flynn, Ryan A., Gavzy, Samuel J., Wu, Lin, Kim, Sangwon V., Hall, Jason A., Miraldi, Emily R., Ng, Charles P., Rigo, Frank, Meadows, Sarah, Montoya, Nina R., Herrera, Natalia G., Domingos, Ana I., Rastinejad, Fraydoon, Myers, Richard M., Fuller-Pace, Frances V., Bonneau, Richard, Chang, Howard Y., Acuto, Oreste, Littman, Dan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762670/
https://ncbi.nlm.nih.gov/pubmed/26675721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados