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5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors

Early metastasis is still the most recalcitrant factor in the treatment of lung cancer patients. By analyzing the structures and comparing the docking scores of the known pharmacophores, the authors of this paper designed 5-(bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA)...

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Bibliografische gegevens
Gepubliceerd in:Drug Des Devel Ther
Hoofdauteurs: Gan, Taiping, Wang, Yuji, Zhao, Ming, Wu, Jianhui, Yang, Jian, Peng, Shiqi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762582/
https://ncbi.nlm.nih.gov/pubmed/26937173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93570
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