5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors

Early metastasis is still the most recalcitrant factor in the treatment of lung cancer patients. By analyzing the structures and comparing the docking scores of the known pharmacophores, the authors of this paper designed 5-(bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA)...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Gan, Taiping, Wang, Yuji, Zhao, Ming, Wu, Jianhui, Yang, Jian, Peng, Shiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762582/
https://ncbi.nlm.nih.gov/pubmed/26937173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93570
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