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Phosphorylation dependent activation of the ESCRT function of ALIX in cytokinetic abscission and retroviral budding

The modular adaptor protein ALIX is a key player in multiple ESCRT-III-mediated membrane remodeling processes. ALIX is normally present in a closed conformation due to an intramolecular interaction that renders ALIX unable to perform its ESCRT functions. Here we demonstrate that M phase-specific pho...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Sun, Sheng, Sun, Le, Zhou, Xi, Wu, Chuanfen, Wang, Ruoning, Lin, Sue-Hwa, Kuang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762455/
https://ncbi.nlm.nih.gov/pubmed/26859355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.01.001
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