Activation of the Retroviral Budding Factor ALIX

The cellular ALIX protein functions within the ESCRT pathway to facilitate intralumenal endosomal vesicle formation, the abscission stage of cytokinesis, and enveloped virus budding. Here, we report that the C-terminal proline-rich region (PRR) of ALIX folds back against the upstream domains and aut...

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Detalhes bibliográficos
Main Authors: Zhai, Qianting, Landesman, Michael B., Chung, Hyo-Young, Dierkers, Adam, Jeffries, Cy M., Trewhella, Jill, Hill, Christopher P., Sundquist, Wesley I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165844/
https://ncbi.nlm.nih.gov/pubmed/21715492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02653-10
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