Glucose is a key driver for GLUT1-mediated nanoparticles internalization in breast cancer cells

The mesenchymal state in cancer is usually associated with poor prognosis due to the metastatic predisposition and the hyper-activated metabolism. Exploiting cell glucose metabolism we propose a new method to detect mesenchymal-like cancer cells. We demonstrate that the uptake of glucose-coated magn...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Venturelli, Leonardo, Nappini, Silvia, Bulfoni, Michela, Gianfranceschi, Giuseppe, Dal Zilio, Simone, Coceano, Giovanna, Del Ben, Fabio, Turetta, Matteo, Scoles, Giacinto, Vaccari, Lisa, Cesselli, Daniela, Cojoc, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761954/
https://ncbi.nlm.nih.gov/pubmed/26899926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21629
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