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Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons

Although the essential role of protein kinase B (PKB)/Akt in cell survival signaling has been clearly established, the mechanism by which Akt mediates the cellular response to hydrogen peroxide (H(2)O(2))-induced oxidative stress remains unclear. We demonstrated that Akt attenuated neuronal apoptosi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Ji Hye, Kim, Chung Kwon, Lee, Sang Bae, Lee, Kyung-Hoon, Cho, Sung-Woo, Ahn, Jee-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761890/
https://ncbi.nlm.nih.gov/pubmed/26899247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21857
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