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Threonine aldolases: perspectives in engineering and screening the enzymes with enhanced substrate and stereo specificities

Threonine aldolases have emerged as a powerful tool for asymmetric carbon-carbon bond formation. These enzymes catalyse the unnatural aldol condensation of different aldehydes and glycine to produce highly valuable β-hydroxy-α-amino acids with complete stereocontrol at the α-carbon and moderate spec...

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Dades bibliogràfiques
Publicat a:Appl Microbiol Biotechnol
Autor principal: Fesko, Kateryna
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761611/
https://ncbi.nlm.nih.gov/pubmed/26810201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-015-7218-5
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