Extensive CD4 and CD8 T-cell cross-reactivity between alphaherpesviruses()

The alphaherpesvirinae subfamily includes HSV types 1 and 2 and the sequence-divergent pathogen varicella zoster virus (VZV). T cells, controlled by TCR and HLA molecules that tolerate limited epitope amino acid variation, might cross-react between these microbes. We show that memory PBMC expansion...

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Bibliographic Details
Published in:J Immunol
Main Authors: Jing, Lichen, Laing, Kerry J., Dong, Lichun, Russell, Ronnie M., Barlow, Russell S., Haas, Juergen G., Ramchandani, Meena S., Johnston, Christine, Buus, Soren, Redwood, Alec J., White, Katie D., Mallal, Simon A., Phillips, Elizabeth J., Posavad, Christine M., Wald, Anna, Koelle, David M.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761520/
https://ncbi.nlm.nih.gov/pubmed/26810224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502366
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