Extensive CD4 and CD8 T-cell cross-reactivity between alphaherpesviruses()

The alphaherpesvirinae subfamily includes HSV types 1 and 2 and the sequence-divergent pathogen varicella zoster virus (VZV). T cells, controlled by TCR and HLA molecules that tolerate limited epitope amino acid variation, might cross-react between these microbes. We show that memory PBMC expansion...

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Pubblicato in:J Immunol
Autori principali: Jing, Lichen, Laing, Kerry J., Dong, Lichun, Russell, Ronnie M., Barlow, Russell S., Haas, Juergen G., Ramchandani, Meena S., Johnston, Christine, Buus, Soren, Redwood, Alec J., White, Katie D., Mallal, Simon A., Phillips, Elizabeth J., Posavad, Christine M., Wald, Anna, Koelle, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761520/
https://ncbi.nlm.nih.gov/pubmed/26810224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502366
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