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NFAT transcription factors promote the generation of follicular helper T cells in response to acute viral infection

Follicular helper T (Tfh) cells provide B cell help in germinal center reactions that support class switching, somatic hypermutation, and the generation of high-affinity antibodies. Here we show that deficiency in NFAT1 and NFAT2 in CD4(+) T cells leads to impaired germinal center reactions upon vir...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Martinez, Gustavo J., Hu, Joyce K., Pereira, Renata M., Crampton, Jordan S., Togher, Susan, Bild, Nicholas, Crotty, Shane, Rao, Anjana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761453/
https://ncbi.nlm.nih.gov/pubmed/26851216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501841
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