Dependence of Proximal GC Boxes and Binding Transcription Factors in the Regulation of Basal and Valproic Acid-Induced Expression of t-PA

Objective. Endothelial tissue-type plasminogen activator (t-PA) release is a pivotal response to protect the circulation from occluding thrombosis. We have shown that the t-PA gene is epigenetically regulated and greatly induced by the histone deacetylase (HDAC) inhibitor valproic acid (VPA). We now...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Vasc Med
Hlavní autoři: Ulfhammer, Erik, Larsson, Pia, Magnusson, Mia, Karlsson, Lena, Bergh, Niklas, Jern, Sverker
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761389/
https://ncbi.nlm.nih.gov/pubmed/26966581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7928681
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky